Journal of Applied Medical Sciences

Comparative Study of Efficacy of Local Preoperative Mitomycin C (MMC) Injection to Intra Operative Application of MMC in the Prevention of Pterygium Recurrence after Surgical Removal

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  • Abstract


    Pterygium is an external eye disease that causes eye’s redness and irritation and affects vision in severe cases. Mitomycin C (MMC) is used in Pterygium excision surgery to reduce the recurrence rate. This study compares the efficiency of preoperative sub conjunctiva MMC injection in Pterygium excision vs. intra-operative topical conjunctiva MMC application. 30 eyes were randomly allocated into two groups, 15 eyes for each group. The collected data were analyzed by SPSS program and comparison between both groups in recurrence and complications rates was done by Chi-Square test and P value, with P value of less than 0.05 was considered important statistically. The study showed that no difference of recurrence rates of Pterygium between sub conjunctiva injection of MMC 24 hours preoperatively and its local application intra-operatively, otherwise sub conjunctiva injection of MMC preoperatively is more irritating and patients are less comfort than those who have MMC local application intraoperatively.


    Keywords: MMC, Pterygium.