Pterygium is an external eye disease that
causes eye’s redness and irritation and affects vision in severe cases.
Mitomycin C (MMC) is used in Pterygium excision surgery to reduce the
recurrence rate. This study compares the efficiency of preoperative sub
conjunctiva MMC injection in Pterygium excision vs. intra-operative topical
conjunctiva MMC application. 30 eyes were randomly allocated into two groups,
15 eyes for each group. The collected data were analyzed by SPSS program and
comparison between both groups in recurrence and complications rates was done
by Chi-Square test and P value, with P value of less than 0.05 was considered
important statistically. The study showed that no difference of recurrence
rates of Pterygium between sub conjunctiva injection of MMC 24 hours
preoperatively and its local application intra-operatively, otherwise sub
conjunctiva injection of MMC preoperatively is more irritating and patients are
less comfort than those who have MMC local application intraoperatively.
Keywords: MMC, Pterygium.