Infertility is admittedly a complicated problem leading to psychological, social and environmental consequences worldwide. Even though in ancient India, it was considered as a curse of God dilated to biological problem, now it is widely connected with life style, custom and individual habits. The rate of infertility was too low in 1900 and compared with this base year, it has now increased up to 71%, due to various factors like environment, employment, marital life. There is also, no difference in the causes of infertility between male and female. In many studies in India, Indonesia, Philippines, Turkey and Iran, there is a considerable difference in the quality of life (QoL) of an infertile couple. Infertile females were more educated, but they are equally more passionate, psychologically isolated, blamed and less healthy even showing tendency of suicide than their male counterparts. This study refers to lifestyle of infertile couple undergoing IVF treatment which will be a helpful tool to identify the patient in terms of QoL followed by him or her. Demographic factors related to the seven dimensions of Roy’s Adaptation Method of QoL studied using R programming and SPSS. Principle Component Analysis is employed to distinguish the independent factors, and multivariate analytic results are also deployed.