This study aims to find whether there is a relationship between stock returns and financial ratios of banks traded in Borsa Istanbul. It is important to introduce this relationship for investors to make an investment decision and also to suggest which financial ratios are more important. For this purpose, quarterly financial ratio data of the selected banks and stock exchange data between 2002Q1-2013Q2 are analyzed by Panel Data Method. As a result of the analysis, all the ratios except for the profitability measuring data show significant results at 5 % significance level. A negative relationship is seen between the ratio of total credits and ratio of assets to total assets measuring the asset quality and the ratio of liquid assets to total assets measuring liquidity position.