At the heart of clinical governance’s strategies, is a strong commitment to the principles of quality and safety. Proactive risk management is an essential tool to enhance patient safety. The present study aims to map the existing organizational climate-in terms of clinical governance in the hospital sector in Greece. The factor “A planned and integrated Quality Insurance (QI) programme and proactive risk management” is analysed in detail. It is a cross-sectional study using factor and correlation analysis, conducted for all categories of employees working in a public and a private hospital. The Clinical Governance Climate Questionnaire (CGCQ) was used with a sample size of 459 employees. The response rate was 72%. The collection of survey data held within a period of four months (May 2012 to August 2012). The study population was not supportive to the climate associated with the research topic. Statistically significant relationships between gender, age, years of experience, legal status of the hospital and the above factor were found. Management may utilize the views of the aforementioned categories of employees, in order to improve the climate of quality and develop a culture of patient safety.