Nurse turnover is associated with financial losses to health care organizations and negative influence on staff morale and the delivery of quality service. Increasing nurse retention is, therefore, important in enhancing performance of healthcare organizations and the provision of quality health service. Traditional approaches used to increase nurse retention include improved remuneration and enhanced working conditions. However the question on the influence of leadership personality and culture on nurse retention is not fully understood. The objective of this study was to evaluate the influence of leadership personality and culture on nurse retention. The study involved a qualitative case study assessment of 70 case studies obtained from four different online databases. The outcome of the study indicated that leadership culture significantly (p=0.037) influence nurse retention. It was observed that leadership culture account for 18.3% of nurse retention level. Leadership cultures such as leadership-as-coordination and leadership by example was shown to have significantly higher positive influence on nurse retention (p=0.022 and p=0.041 respectively) compared to the influence of the culture of leadership-as-dominance. The study recommends that adoption of leadership-as-coordination and leadership by example as a means of increasing nursesí retention.